RSV: Are we prepared to protect the vulnerable?

The respiratory syncytial virus (RSV) can affect anyone, but most people typically get it initially during infancy or as toddlers. RSV typically causes mild illness, but it is contagious and can lead to severe illnesses affecting the lungs, particularly for infants younger than 6 months and older adults.

Drawing on Singapore research, Dr. Leong Hoe Nam, an infectious disease physician at Rophi Clinic, shares that the infection often begins with cold-like symptoms, including nasal congestion, runny nose, sore throat, and fever.

In the Philippines, cases of RSV tend to rise between May and November and is considered as the most common respiratory virus in hospitalized children below two years old. The Research Institute for Tropical Medicine (RITM), through its Philippine National Influenza Center (PNIC), leads the RSV Surveillance Pilot Project in partnership with the Department of Health (DOH) and the World Health Organization (WHO).

This RITM-led initiative that launched in 2021 has established hospital sentinel sites across Luzon, Visayas, and Mindanao to monitor RSV activity and understand its seasonality. These sites collect and analyze data to evaluate the burden of RSV among hospitalized children, helping inform public health strategies and vaccination efforts.

The Philippines is also recognized as a key contributor to the WHO Global RSV Surveillance, becoming the first among six low- and lower-middle-income countries (LLMIC) to produce disease burden estimates for RSV. These efforts are crucial in shaping preventive strategies, including vaccination and maternal immunization, which offer significant protection against severe RSV complications.

THE IMPACT OF RSV ON VULNERABLE POPULATIONS

Anyone is susceptible to RSV, but doctors know it can be more serious for adults over 60 – including those with underlying medical conditions – and babies under six months of age. Additional risk factors include chronic health problems like asthma, COPD, or congestive heart failure for older adults. For children, conditions such as neuromuscular disorders, chronic lung disease, congenital heart disease, or weakened immune systems can increase additional risk.

As described in a review of scientific literature, majority of infants with severe RSV were born at term and previously healthy.

Dr. Leong highlighted that the infection can lead to lower respiratory infections. “These infections are particularly challenging for individuals over 65 due to their weakened immune systems. Moreover, those with pre-existing medical conditions, especially heart or lung-related issues, are more vulnerable to complications from RSV,” he said. 

RSV also poses significant risks to residents of long-term care facilities and those with compromised immune systems, including transplant recipients and individuals on steroid therapy or other immunosuppressants. In the most severe cases, RSV may even be fatal, Dr. Leong added.

REDUCING RSV RISKS

RSV spreads mainly through droplets from an infected person’s coughs and sneezes, which can come into contact with another person’s eyes, nose or mouth. It can also be transmitted through contact with contaminated surfaces.

To prevent the spread of RSV, Dr. Leong emphasized the importance of practicing good hand hygiene, wearing masks and maintaining a safe distance (of 2m or more) from unwell people. He also advised against sharing items like cups, as the virus can survive on surfaces for several hours. 

The Centers for Disease Control and Prevention (CDC) stated that there is currently no effective treatment for RSV, so prevention through vaccination is key to minimizing complications from the illness. 

Dr. Rontgene Solante, Head of Infectious Disease at San Lazaro Hospital, said in a presentation held last January before healthcare professionals that “RSV is a viral infection that can be deadly, and since it commands a great rate of morbidity and mortality, there is no other available treatment than prevention through vaccination. Vaccine providers have been supporting the local health sector in addressing these challenges by raising awareness on the illness and improving vaccine availability. This enhances the landscape of RSV prevention to a better and more achievable outcome and increased patient survival.”

ADOPTING A PREVENTIVE APPROACH

According to Dr. Leong, vaccination works by stimulating the immune system to produce antibodies. The RSV vaccine contains a protein from the respiratory syncytial virus. When administered, it triggers the immune system to respond, creating protection that helps stave off severe infection.

The doctor noted the importance of adopting a prevention mindset, aligning with the goal of protecting loved ones from severe RSV complications.

“RSV is a life-threatening infection that can cause significant despair for families,” said Dr. Leong. “Doctors may be limited in their treatment options, making prevention through vaccination one of the most effective methods to safeguard health.”

Maternal immunization is a well-established and crucial public health strategy. By administering vaccines during pregnancy, mothers can pass on antibodies to their unborn children through the placenta that can protect them in the early vulnerable period after birth.

The public is advised to consult with their physicians about the risks of RSV and how to protect vulnerable people, including RSV vaccination.


The article is brought to you by Pfizer Philippines. The contents represent the opinions and experience of respective individuals and do not necessarily represent the views or recommendation of Pfizer. The information provided is for educational and communication purposes only and it should not be construed as personal medical advice. Information published in this article is not intended to replace, supplant or augment a consultation with a health professional regarding the reader’s own medical care.

References:

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Centers for Disease Control and Prevention. RSV in Infants and Young Children. https://www.cdc.gov/rsv/infants-young-children/index.html. Published August 30, 2024. Accessed February 2025

Mazur N, Caballero MT, Nunes MC. Severe respiratory syncytial virus infection in children: burden, management, and emerging therapies. Lancet. 2024;404:1 143-1156

Centers for Disease Control and Prevention. RSV Causes. https://www.cdc.gov/rsv/causes/index.html. Published August 30, 2024. Accessed December 2024

Centers for Disease Control and Prevention. RSV Symptoms. https://www.cdc.gov/rsv/symptoms/index.html. Published August 30, 2024. Accessed December 2024

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Eastern Melbourne PHN. NCIRS releases suite of new and updated RSV resources. https://emphn.org.au/news/ncirs-releases-suite-of-new-and-updated-rsv-resources/. Published February 17, 2025. Accessed February 19, 2025

Centers for Disease Control and Prevention. RSV Transmission. https://www.cdc.gov/rsv/about/transmission.html. Published August 30, 2024. Accessed December 2024

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Tam CC, Yeo KT, Tee N, et al. Burden and Cost of Hospitalization for Respiratory Syncytial Virus in Young Children, Singapore. Emerg Infect Dis. 2020;26:1 489-1496 

Channel News Asia. More than just a cold: Understanding the respiratory syncytial virus. https://www.channelnewsasia.com/advertorial/more-just-cold-understanding-respiratory-syncytial-virus-4563381Published October 15,2024. Accessed December 2024

Research Institute for Tropical Medicine. National Influenza Center leads pilot stakeholders’ meeting for RSV. https://ritm.gov.ph/1strsvstakeholdersmeeting/. Published September 24, 2024. Accessed December 2024